Posted On 2022-03-09

Guest Editor: Dr. Ha-Neui Kim

Assistant Professor, Center for Musculoskeletal Disease Research and Center for Osteoporosis and Metabolic Bone Diseases, Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.



Dear Colleagues,

Soon after the attainment of peak bone mass, the balance between bone formation and bone resorption begins to progressively shift in favor of the latter, in both women and men. Thus, better understanding the cellular and molecular mechanism(s) involved in differentiation and activation of the skeletal cells are important for development of novel therapies to treat skeletal diseases caused by old age.
We invite researchers to submit original research and review articles covering significant developments in the cellular senescence, mitochondrial dysfunction, and oxidative stress of bone cells, as well as novel medicines or strategies that hold promise in the prevention and/or treatment of skeletal aging and diseases. In particular, we welcome research covering novel molecular mechanism, new tools on bone research, or any animal studies with clinical relevance.

Dr. Ha-Neui Kim
Guest Editor


Manuscript Submission Information

Manuscripts should be submitted online at through the online submission system. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, Review articles as well as Therapeutic Brief are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. APT is an international peer-reviewed open access quarterly journal published by ANT.

Please visit the Instructions for Authors page before submitting a manuscript. Considering limited grants for some researchers, Dr. Ha-Neui Kim and the editorial office made the decision that Article Processing Charges will be fully exempted, which means that there is NOT any manuscript processing or publication fees for your article once accepted after standard peer-review.


Submission Deadline

December 31st, 2023



Aging, bone, osteoclasts, osteoblasts, osteocytes, senescence, mitochondria, oxidative stress.



Xu Feng, Professor, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Zhiwen Luo, Huashan Hospital, Fudan University (Sports Medicine), Shanghai, China.
Yueqi Chen, Department of Orthopedics, Southwest Hospital, National & Regional United Engineering Laboratory of Tissue Engineering, Army Military Medical University (Third Military Medical University), Chongqing, China.



June Wong, Managing Editor,
Alan Zhou, Assistant Editor,


Updated on June 27, 2022

Table of Contents


Zihan Deng, Chuan Yang, Yueqi Chen
Received: Monday, March 6, 2023      Published: Wednesday, June 28, 2023

Mini Review

Renwen Wan, Hanli Zhang, Shan Liu, Chunmeng Jiao, Hui Chen, Zhiwen Luo, Xiliang Shang
Received: Thursday, February 23, 2023      Published: Wednesday, June 28, 2023

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