Coronary artery stenosis regression by long-term standard dose statin therapy in middle-aged and elderly patients: Report and analysis of 31 cases

Abstract

Objective: To study the possibility and characteristics of long-term standard dose statin-induced stenosis regression in middle-aged and elderly patients with coronary heart disease (CHD).

Methods: The study patients were those with CHD admitted to our hospital from 2010 to 2019. All patients underwent computed tomography angiography (CTA) scanning and were diagnosed with a regression of stenosis.

Results: Thirty-one patients (24 males and 7 females) with an average age of 64.7±1.8 years were reexamined by CTA at a mean of 18.6±1.9 months after the initial examination. The left anterior descending (LAD) coronal artery stenoses were significant regressed.

Conclusion: In middle-aged to elderly patients with CHD, a long-term and standard dose statin treatment may lead to the regression of coronary artery stenosis.

Key Words: Coronary atherosclerosis, statin, coronary CT angiography, middle-aged and elderly.