Most Viewed Articles
Drug nanotargeting for treatment of neurodegeneration and aging
Joseph S. D'Arrigo
Published: Tuesday, June 29, 2021
Viewed: 86706
The potential of GHK as an anti-aging peptide
Warren Ladiges, Yan Dou, Amanda Lee, Lida Zhu, John Morton
Published: Friday, March 27, 2020
Viewed: 30493
Irreversible effects of anticholinergic withdrawal in the elderly: a case report
Charisse Chehovich, Claudia Lee, Tammie Lee Demler
Published: Tuesday, June 29, 2021
Viewed: 17161
The potential of astaxanthin as a natural compound for decelerating skin aging: an update review
Teresa Liliana Wargasetia, Ratna Sariharyanti, Hana Ratnawati
Published: Thursday, December 26, 2024
Viewed: 12494
Sleep-deprived cognitive impairment in aging mice is alleviated by rapamycin
Warren Ladiges, Kishore Mukherjee, Amanda Lee, Lida Zhu, Martin Darvas
Published: Monday, December 30, 2019
Viewed: 9899
Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging
Warren Ladiges, Yuji Ikeno, Liang Wang
Published: Friday, March 27, 2020
Viewed: 9670
Leucine metabolite β-hydroxy-β-methyl butyrate (HMB) supplementation on muscle mass during resistance training in older subjects: meta-analysis
Guangqin Zou, Quan Wang, Hua Wan, Xiang Lu, Wei Gao
Published: Wednesday, March 30, 2022
Viewed: 9641
The rationale for testing drug combinations in aging intervention studies
Kavita C Sharma, Juan Wang, Zhou Jiang, Jenna Klug, Martin Darvas, Denise M Imai, Timothy Snider, Laura Niedernhofer, Warren C Ladiges
Published: Monday, December 30, 2019
Viewed: 9431
Novel LMNA mutations in Greek and Myanmar Patients with Progeroid Features and Cardiac Manifestations
Junko Oshima, Renuka Kandhaya-Pillai, Fuki M Hisama, Stephanie A Bucks, Soe Yarzar, Haroula Korovou, George M Martin
Published: Monday, June 29, 2020
Viewed: 9342
Highly expressed ribosomal protein L34 predicts poor prognosis in acute myeloid leukemia and could be a potential therapy target
Liang Wang, Jing Yang, Henan Wang, Weida Wang, Xiaojie Liang
Published: Friday, March 27, 2020
Viewed: 8740
QuPath. A new digital imaging tool for geropathology
Warren Ladiges, Amanda Lee, Zhou Jiang, Lida Zhu
Published: Monday, June 29, 2020
Viewed: 8663
Development of a Geropathology Grading Platform for nonhuman primates
Warren Ladiges, Katie J Olstad, Denise M Imai, Rebekah I Keesler, Rachel Reader, John H Morrison, Jeffery A Roberts, John P Capitanio, Elizabeth S Didier, Marcelo J Kuroda, Heather Simmons, Shabnam Salimi, Julie A Mattison, Yuji Ikeno
Published: Friday, March 27, 2020
Viewed: 8630
LINC00271 inhibits epithelial-mesenchymal transition of papillary thyroid cancer cells by downregulating trefoil factor 3 expression
Jianda Dong, Pihong Li, Xiaoyu Pan, Zhouci Zheng, Yihan Sun, Yifan Han
Published: Monday, June 29, 2020
Viewed: 8617
Aging pet cats develop neuropathology similar to human Alzheimer’s disease
Warren Ladiges, Jenna Klug, Jessica M. Snyder, Martin Darvas, Denise M. Imai, Molly Church, Caitlin Latimer, C . Dirk Keene
Published: Tuesday, September 29, 2020
Viewed: 8589
The CB6F1 mouse is a model for studying cognition and brain morphometry with increasing age
Warren Ladiges, Davika Gandhay, Christina Pettan Brewer
Published: Wednesday, March 29, 2023
Viewed: 8522
Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice
Madeline G. Roman, Lisa C. Flores, Geneva M. Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Yidong Bai, Thomas L. Saunders, Yuji Ikeno
Published: Friday, March 27, 2020
Viewed: 8464
Clinical diagnosis and treatment of primary small intestinal lymphoma
Guitian Huang
Published: Thursday, September 30, 2021
Viewed: 8291
Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice
Kaitlin Nickel, Lida Zhu, Ruby Mangalindan, Jessica M. Snyder, Jeremy Whitson, Maryia Sweetwyne, Ana P. Valencia, Jenna Klug, Zhou Jiang, David J. Marcinek, Peter Rabinovitch, Warren Ladiges, Matthew Tucker
Published: Friday, September 30, 2022
Viewed: 8196
Progress on the study of fibroblast growth factors as novel therapeutics in post-stroke cognitive impairment
Hong Fan, Mengqi Li
Published: Thursday, September 30, 2021
Viewed: 8162
Sex-dependent lifespan extension of ApcMin/+ FAP mice by chronic mTOR inhibition
Manish Parihar, Sherry G Dodds, Marty Javors, Randy Strong, Paul Hasty, Zelton Dave Sharp
Published: Thursday, December 31, 2020
Viewed: 7897
Interfering with miR-24 alleviates rotenone-induced dopaminergic neuron injury via enhancing autophagy by upregulating DJ-1
Fengrui Li, Biao Ge, Hairong Wu, Dan Shao, Shulin Li
Published: Monday, December 30, 2019
Viewed: 7873
Drug-Induced Hemolytic Crisis During Ibrutinib plus Venetoclax for the Treatment of Mantle-Cell Lymphoma: A Rare Hematologic Adverse Reaction
Xin Wen, Liang Wang, Yingzhi He, Shan Wang
Published: Monday, December 30, 2019
Viewed: 7847
Eosinophilic crystalline pneumonia, an age-related lesion in mice
Jenna J Klug, Jessica M Snyder
Published: Thursday, December 31, 2020
Viewed: 7798
Molecular hydrogen may activate the transcription factor Nrf2 to alleviate oxidative stress through the hydrogen-targeted porphyrin
Shigeo Ohta
Published: Tuesday, May 23, 2023
Viewed: 7770
Molecular hydrogen may activate the transcription factor Nrf2 to alleviate oxidative stress through the hydrogen-targeted porphyrin
Shigeo Ohta
Published: Tuesday, May 23, 2023
Viewed: 7770
Resilience to aging is a heterogeneous characteristic defined by physical stressors
Haoyi Lei, Derek M. Huffman, Adam B. Salmon, Nathan K. LeBrasseur, Christy Carter, Arlan Richardson, Steve Austad, Warren Ladiges
Published: Wednesday, March 30, 2022
Viewed: 7757
Thioredoxin and aging: What have we learned from the survival studies?
Lisa C. Flores, Madeline G. Roman, Geneva M. Cunningham, Christie Cheng, Colton Allen, Gene Borden Hubbard, Yidong Bai, Thomas L. Saunders, Yuji Ikeno
Published: Tuesday, September 29, 2020
Viewed: 7734
Down-regulation of miR-181a promotes microglial M1 polarization through increasing expression of NDRG2
Bo Zhou, Yali Niu, Chunxiao Wan, Rui wu, Heying Sun, Danqing Lu
Published: Friday, March 27, 2020
Viewed: 7682
Progress in drug treatment of elderly chronic heart failure
Feng Liu, Siting Zhang
Published: Thursday, December 31, 2020
Viewed: 7604
A model for studying cutaneous wound healing and resilience to aging: Ear punch biopsy in old mice
Warren Ladiges, Zhou Jiang, Jessie Chen, Juan Wang, Ruby Mangalindan, Lida Zhu
Published: Tuesday, September 29, 2020
Viewed: 7584
Mitochondrial-targeted methionine sulfoxide reductase overexpression increases the production of oxidative stress in mitochondria from skeletal muscle
Adam B. Salmon, Arunabh Bhattacharya, Daniel Pulliam, Yuhong Liu
Published: Friday, March 27, 2020
Viewed: 7515
MicroRNA-152 suppresses cell proliferation and tumor growth of bladder cancer by targeting KLF5 and MKK7
Liangliang Wang, Yu Hui, Yuhua Huang, Xiang Ding
Published: Monday, December 30, 2019
Viewed: 7498
The cellular senescence unification model and telomerase therapy: To treat all age-related diseases
Steve Liebich
Published: Tuesday, September 29, 2020
Viewed: 7398
Gastrointestinal Disasters of Cetuximab in the Treatment of Metastatic Colorectal Cancer: Mechanism and its Effect on Prognosis
Junfeng Sun, Yue Wu, Haowei Jia, Xinqi Bao, Tianyu Zhu, Ruixin Li, Hongchao Zhao
Published: Monday, June 29, 2020
Viewed: 7332
Time for an Alzheimer’s disease cocktail
Warren Carl Ladiges
Published: Friday, March 27, 2020
Viewed: 7256
A mouse model of sleep deprived neuropathology to study resilience to Alzheimer’s disease
Warren Ladiges, Yan Dou, Jinzi Wu, Lida Zhu, Martin Darvas
Published: Monday, June 29, 2020
Viewed: 7245
Pioglitazone up-regulates MALAT1 and promotes the proliferation of endothelial progenitor cells through increasing c-Myc expression in type 2 diabetes mellitus
Xiaoxu Yang, Chen Hu, Yan Sun
Published: Friday, March 27, 2020
Viewed: 7154
Resilience to acute sleep deprivation is associated with attenuation of hippocampal mediated learning impairment
Warren Ladiges, Amanda Lee, Haoyi Lei, Lida Zhu, Zhou Jiang
Published: Thursday, December 31, 2020
Viewed: 7114
IL-17 regulates the expression of major histocompatibility complex II and VEGF in DLBCL mice on tumor growth
Xin Xu, Ting Wei, Weijie Zhong, Zhigang Zhu, Feng Liu, Qingshan Li
Published: Monday, June 29, 2020
Viewed: 7059
Coronary artery stenosis regression by long-term standard dose statin therapy in middle-aged and elderly patients: Report and analysis of 31 cases
Feng Liu, Zhilei Ren, Chongzhe Yang, Kaihua Huang
Published: Tuesday, September 29, 2020
Viewed: 6957
Di-2-pyridylketone 4, 4-dimethyl-3-thiosemicarbazone effectively induces human colorectal carcinoma cell apoptosis via mTOR pathway
Qianqian Fu, Shengli Wang, Chuyun Zhu, Zhenlong Zhou, Xiaojuan Yu, Yong Zhang
Published: Thursday, September 30, 2021
Viewed: 6861
Guidelines for the Prevention of Coronavirus Pneumonia in Elderly People
Wei Ma, Jun Zhao, Gang Xu, Congrui Feng, Yuluo Chen, Feng Liu
Published: Monday, June 29, 2020
Viewed: 6839
Physical performance is enhanced in old mice fed a short term diet medicated with rapamycin, acarbose, and phenylbutyrate
Warren Ladiges, Megan Ellis, Zhou Jiang
Published: Monday, March 29, 2021
Viewed: 6712
Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging
Michal M. Masternak, Hariom Yadav
Published: Wednesday, March 30, 2022
Viewed: 6688
Finding prodromal frailty in a community-dwelling healthy older cohort by survey of BDNF or hand grip strength classified by BMI
Mitsugu Hachisu, Masahiro Hashizume, Hisashi Kawai, Motonaga Kojima, Yoshinori Fujiwara, Shuichi Obuchi, Mari Kogo, Masayuki Ohbayashi, Noriko Koyama, Miki Takenaka, Kazushige Ihara
Published: Tuesday, September 29, 2020
Viewed: 6666
An immune stress test for resilience to aging: Pneumococcal vaccine response
Warren Ladiges, Ryan Oveson, Zhou Jiang, Michali Izhak, Kavita Sharma
Published: Tuesday, September 29, 2020
Viewed: 6632
Gam-COVID-Vac (Sputnik V): a heterologous adenoviral vector-based COVID-19 vaccine
Shyh Poh Teo, Sanny Zi Lung Choo
Published: Tuesday, June 29, 2021
Viewed: 6533
Negative health effects of low testosterone concentrations in older adults
Chieh Chen, Da-Ming Liao
Published: Thursday, February 29, 2024
Viewed: 6501
The potential of XPO1 inhibitors as a game changer in relapsed/refractory hematologic malignancies
Henan Wang, Liang Wang, Jing Yang
Published: Monday, June 29, 2020
Viewed: 6500
Anti-tumor effect of pcDNA3.1(-)/rMETase-shUCA1 hyaluronic acid-modified G5 polyamidoamine nanoparticles on gastric cancer
Chunying Xie, Zhenxing Huang, Zhaohui Huang, Yanyan Guo, Xue Zhang
Published: Monday, June 29, 2020
Viewed: 6450
Oxidative stress in aging: stayin’ alive?
Lisa C. Flores, Yuji Ikeno
Published: Monday, June 29, 2020
Viewed: 6446
Short-term oral rapamycin prevents age-related learning impairment in mice
Warren Ladiges, Haoyi Lei, Juan Wang, Zhou Jiang
Published: Tuesday, September 29, 2020
Viewed: 6439
Sarcopenia and falls in older adults
Chieh Chen, Daming Liao
Published: Friday, September 30, 2022
Viewed: 6421
Thioredoxin down-regulation in the cytosol in thioredoxin 2 transgenic mice did not have beneficial effects to extend lifespan in male C57BL/6 mice
Lisa C. Flores, Madeline G. Roman, Geneva M. Cunningham, Christie Cheng, Colton Allen, Yidong Bai, Gene B. Hubbard, Yuji Ikeno
Published: Thursday, December 31, 2020
Viewed: 6416
KDClassifier: A urinary proteomic spectra analysis tool based on machine learning for the classification of kidney diseases
Wanjun Zhao, Yong Zhang, Xinming Li, Yonghong Mao, Changwei Wu, Lijun Zhao, Fang Liu, Jingqiang Zhu, Jingqiu Cheng, Hao Yang, Guisen Li
Published: Thursday, September 30, 2021
Viewed: 6408
Association of anemia with rehabilitation outcome for subacute geriatric rehabilitation patients in a secondary hospital in malaysia
Mann Leon Chin, Christopher WS Chan, Huey Ee Chong, Wee Kooi Cheah
Published: Friday, December 31, 2021
Viewed: 6355
Age effect on mesenchymal stem cell properties: A concise review
Tsz Kin Ng, Chong-Bo Chen, Xin Bin, Yuqiang Huang, Herman S. Cheung
Published: Tuesday, May 23, 2023
Viewed: 6345
Age effect on mesenchymal stem cell properties: A concise review
Tsz Kin Ng, Chong-Bo Chen, Xin Bin, Yuqiang Huang, Herman S. Cheung
Published: Tuesday, May 23, 2023
Viewed: 6345
Geropathology. An inside view of biological aging
Warren Ladiges
Published: Wednesday, March 30, 2022
Viewed: 6341
Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study
Eleonora Duregon, Rafael de Cabo, Camila Vieira Ligo Teixeira, Dushani L. Palliyaguru, Annamaria L. Rudderow, Victoria Hoffmann, Michel Bernier, Nathan L. Price, Simonetta Camandola
Published: Thursday, December 31, 2020
Viewed: 6323
Myocardial Cell Aging in the Elderly
Feng Liu, Wenxi Li
Published: Tuesday, September 29, 2020
Viewed: 6290
The critical role of macrophages in ovarian cancer treatment
Yiran Wang, Mingyi Wang
Published: Friday, September 30, 2022
Viewed: 6270
miR-181c inhibits prostatic epithelial cell proliferation caused by chronic non-bacterial prostatitis through down-regulating COX-2
Xiang Ding, Xu Xu, Yuhua Huang, Jianquan Hou, Jinxing Lv
Published: Thursday, December 31, 2020
Viewed: 6259
Neutrophil response to cyclophosphamide predicts resilience to age-related learning impairment
Lida Zhu, Warren Ladiges, Katie Nickel, Marianne Bjorner
Published: Thursday, December 31, 2020
Viewed: 6138
Recent advances in the genetic association between osteoporotic fracture and sarcopenia
Qiaocong Chen, Huiling Lou, Cheng Peng
Published: Monday, March 29, 2021
Viewed: 6098
Nasal type extranodal natural killer/T-cell lymphoma-associated hemophagocytic lymphohistiocytosis: a Case report and literature review
Xuelin Liu, Liqiang Wei, Jing Yang, Jin Ye, Liang Wang
Published: Wednesday, March 30, 2022
Viewed: 6091
A geropathology approach for identifying therapeutic targets to prevent pathological complications of COVID-19
Warren Ladiges, Yuji Ikeno, Liang Wang, Feng Liu
Published: Monday, June 29, 2020
Viewed: 6085
Evidence for an alternative insulin transporter at the blood-brain barrier
Elizabeth M Rhea, William A Banks, Cassidy Noonan
Published: Tuesday, May 23, 2023
Viewed: 6079
Evidence for an alternative insulin transporter at the blood-brain barrier
Elizabeth M Rhea, William A Banks, Cassidy Noonan
Published: Tuesday, May 23, 2023
Viewed: 6079
Application and research progress of BCL2 inhibitors in elderly patients with hematologic malignancies
Liang Wang, Yufan Wang
Published: Thursday, December 31, 2020
Viewed: 6067
The unrecognized potential of pet cats for studying aging and age-related diseases
Warren Ladiges
Published: Friday, December 31, 2021
Viewed: 6035
Safety and efficacy of the Novavax vaccine—a narrative review
Shyh Poh Teo, Sanny Zi Lung Choo
Published: Friday, December 31, 2021
Viewed: 6002
Hepatic steatosis, a lesion reported in captive aged common marmosets
Sebastian Eduardo Carrasco, Olga Lucia Franco-Mahecha
Published: Monday, March 29, 2021
Viewed: 5999
PathoClock and PhysioClock in mice recapitulate human multimorbidity and heterogeneous aging
Warren Ladiges, Shabnam Salimi, Christina Pettan-Brewer
Published: Friday, December 31, 2021
Viewed: 5955
The antidiabetic drug acarbose suppresses age-related lesions in C57BL/6 mice in an organ dependent manner
Zhou Jiang, Sneh Gupta, Warren Ladiges
Published: Tuesday, June 29, 2021
Viewed: 5817
Denosumab for the treatment of osteoporosis
Shyh Poh Teo
Published: Tuesday, September 29, 2020
Viewed: 5784
Chimeric antigen receptor T cell therapy in cancer: Advances and challenges
Yuanzheng Liang, Liang Wang
Published: Thursday, September 30, 2021
Viewed: 5727
Advances in targeting programmed cell death 1/programmed cell death-ligand 1 therapy for hematological malignancies
Liang Wang, Yuanzheng Liang, Wanying Zhao
Published: Friday, December 31, 2021
Viewed: 5725
Senescence of mesenchymal stem cells: implications in extracellular vesicles, miRNAs and their functional and therapeutic potentials
Guangqian Zhou, Liangge He, Mingzhu Li, Zhen Liu, Arshad Ahmed Padhiar
Published: Tuesday, October 17, 2023
Viewed: 5659
Castleman disease with rapidly progressive pemphigus: case report
Liang Wang, Ruiying Fu, Yingzhi He
Published: Thursday, December 31, 2020
Viewed: 5653
Effect of Pilates versus resistance training on physical fitness in older adults
Manisha Ashish Rathi, Khushboo Muthiyan, Reema Joshi, Preeti Gazbare
Published: Thursday, September 12, 2024
Viewed: 5640
Optimal induction treatment regimens for extranodal NK/T-cell lymphoma: lessons learned, challenges, and proposals
Liang Wang, Jing Yang, Ruiying Fu, Xindi Liu, Liqiang Wei
Published: Thursday, December 31, 2020
Viewed: 5629
A fornix infarction causing post-operative anterograde amnesia
Shyh Poh Teo
Published: Tuesday, June 29, 2021
Viewed: 5619
GHK peptide prevents sleep deprived learning impairment in aging mice
Warren Ladiges, Manuela Rosenfeld, Katie Nickel
Published: Wednesday, March 29, 2023
Viewed: 5578
Preventive effect of rehabilitation training therapy on muscle quality in patients with stroke: A retrospective study
Xiang Lu, Dandan Feng, Wei Gao, Can Zhao, Dan Chen, Xiaojing He
Published: Friday, December 31, 2021
Viewed: 5572
The aging immune system. Abstracts presented at the Masoro-Barshop conference on aging, October 13-15, 2021
Warren Ladiges
Published: Friday, December 31, 2021
Viewed: 5493
Arthritis as an adverse event of special interest post COVID-19 vaccine implementation
Shyh Poh Teo
Published: Monday, March 29, 2021
Viewed: 5443
Immunotherapy: the blockbuster in cancer treatment
Liang Wang
Published: Tuesday, September 29, 2020
Viewed: 5434
A mouse model of naturally occurring age-related cognitive impairment
Sara Daneshjoo, Jualiana Moreno, Manuela Rosenfeld, Joo Young Park, Martin Darvas, Warren Ladiges
Published: Friday, September 30, 2022
Viewed: 5346
Precision aging. Human lifespan has intrinsic limits but measurable outcomes
Warren Ladiges
Published: Tuesday, June 29, 2021
Viewed: 5340
Vitiligo as a potential degenerative disease: from oxidative stress to cellular senescence
Yaojun Wang, Jiaoni Chi, Tao Wang, Yue Zhang, Zhimin Li, Jie Chen, Haixia Liu, Qiang Li
Published: Thursday, June 30, 2022
Viewed: 5339
Thioredoxin – a magic bullet or a double-edged sword for mammalian aging?
Yuji Ikeno
Published: Tuesday, June 29, 2021
Viewed: 5287
Cardiac arrest in an older male patient treated with flecainide for atrial fibrillation
Tiziana Ciarambino, Rosario Bottone, Gennaro Sansone, Mauro Giordano
Published: Tuesday, June 29, 2021
Viewed: 5275
Pharmaceutical interventions to slow human aging. Are we ready for cocktails?
Warren Ladiges, Manuela Rosenfeld
Published: Thursday, June 30, 2022
Viewed: 5249
Mouse modeling for anxiety disorders in older adults
Martin Darvas, Warren Ladiges, Nadia Postupna
Published: Thursday, September 30, 2021
Viewed: 5216
Mechanisms of autophagy regulation by adiponectin
Xin Xu, Chan Rong
Published: Friday, December 31, 2021
Viewed: 5119
2020 Reviewer Acknowledgment
Editorial Office of Aging Pathobiology and Therapeutics
Published: Thursday, December 31, 2020
Viewed: 5081
Older female relatives of Covid-19 patients have an un-satisfactory perception of emergency room performance by clinical staff
Tiziana Ciarambino, Luigia Palmiero, Rosario Bottone, Federico Schettini, Luigi Elio Adinolfi, Mauro Giordano
Published: Tuesday, June 29, 2021
Viewed: 5045
Technical development of senescence-associated β-galactosidase staining in frozen kidney tissue of Sprague Dawley rat
Yuji Ikeno, Ganga Tandukar, Lisa C. Flores, Colton Allen, Yidong Bai
Published: Tuesday, September 24, 2024
Viewed: 4865
Targeting IGF1R signaling for brain aging and Alzheimer’s disease
Warren Ladiges, Joo Young Park, Martin Darvas
Published: Thursday, December 29, 2022
Viewed: 4823
Human microbiota alterations — emerging predictors of renal diseases and kidney-specific aging
Chao Zhao, Miaomiao Pan, Ming Zhang, Xingyu Rong
Published: Wednesday, March 29, 2023
Viewed: 4817
Role of microRNAs in skin aging and its potential therapeutic interventions
Deusdedit Tusubira, Ashikha Shirin Usman PP, Durairaj Sekar
Published: Tuesday, June 25, 2024
Viewed: 4716
Role of microRNAs in skin aging and its potential therapeutic interventions
Deusdedit Tusubira, Ashikha Shirin Usman PP, Durairaj Sekar
Published: Tuesday, June 25, 2024
Viewed: 4716
Role of fibro-adipogenic progenitors in skeletal muscle aging
Renwen Wan, Hanli Zhang, Shan Liu, Chunmeng Jiao, Hui Chen, Zhiwen Luo, Xiliang Shang
Published: Wednesday, June 28, 2023
Viewed: 4694
Role of fibro-adipogenic progenitors in skeletal muscle aging
Renwen Wan, Hanli Zhang, Shan Liu, Chunmeng Jiao, Hui Chen, Zhiwen Luo, Xiliang Shang
Published: Wednesday, June 28, 2023
Viewed: 4694
Targeted regulation of senescence-associated secretory phenotype with an aptamer-conjugated activatable senomorphic
Yanlan Liu, Yuqi Xie, Jili Li, Pingyu Wu, Linlin Wang, Donghui Hong, Jian Wang
Published: Wednesday, June 28, 2023
Viewed: 4692
Targeted regulation of senescence-associated secretory phenotype with an aptamer-conjugated activatable senomorphic
Yanlan Liu, Yuqi Xie, Jili Li, Pingyu Wu, Linlin Wang, Donghui Hong, Jian Wang
Published: Wednesday, June 28, 2023
Viewed: 4692
The house cricket is an unrecognized but potentially powerful model for aging intervention studies
Warren Ladiges, Gerald Yu Liao, Manuela Rosenfeld, Jackson Wezeman
Published: Tuesday, March 19, 2024
Viewed: 4684
On the growth of young neurologists—an interview with Prof. Louis R. Caplan
Qi Qin
Published: Friday, September 30, 2022
Viewed: 4605
Sex matters in aging. The canagliflozin story
Warren Ladiges, Jackson Wezeman
Published: Friday, September 30, 2022
Viewed: 4569
Research progress in the PD-1/PD-L1 pathway and IL-17A in lymphomas
Li Yang, Xin Xu
Published: Thursday, June 30, 2022
Viewed: 4538
The naturally occurring peptide GHK reverses age-related fibrosis by modulating myofibroblast function
Warren Ladiges, Qianpei He, Jordan Mazzola
Published: Thursday, December 26, 2024
Viewed: 4448
Targeting metabolism through exercise and nutrition to rejuvenate an aging immune system
Brandt D. Pence
Published: Friday, September 30, 2022
Viewed: 4338
Behavioral and neuropathological features of Alzheimer’s disease are attenuated in 5xFAD mice treated with intranasal GHK peptide
Matthew Tucker, Gerald Yu Liao, Joo Young Park, Manuela Rosenfeld, Jackson Wezeman, Ruby Mangalindan, Dan Ratner, Martin Darvas, Warren Ladiges, Addison Keely
Published: Monday, August 26, 2024
Viewed: 4207
Sotrovimab for treatment of COVID-19 infections
Shyh Poh Teo
Published: Thursday, June 30, 2022
Viewed: 4203
A reappraisal of the measured concentration of voriconazole based on plasma albumin concentration during its therapeutic drug monitoring
Fangmin Xu, Yexuan Wang, Xiaoshan Zhang, Junhui Yu, Liwen Zhang, Xuben Yu, Haina Zhang
Published: Thursday, June 30, 2022
Viewed: 4164
A review of variable risk factors affecting the development of mild cognitive impairment in older adults
Chenghui Zhang, Hong Fan, Mengqi Li
Published: Tuesday, December 26, 2023
Viewed: 4154
Withania somnifera: a promising neuroprotective ally against Alzheimer's disease
Rajaram Mohapatra, Pratikeswar Panda
Published: Thursday, December 26, 2024
Viewed: 4141
Withania somnifera: a promising neuroprotective ally against Alzheimer's disease
Rajaram Mohapatra, Pratikeswar Panda
Published: Thursday, December 26, 2024
Viewed: 4141
Molecular docking and ADMET analysis of coenzyme Q10 as a potential therapeutic agent for Alzheimer's disease
Abdullah Al Noman, Pranab Dev Sharma, Tasmia Jahin Mim, Md Al Azad, Himanshu Sharma
Published: Thursday, December 26, 2024
Viewed: 4138
Molecular docking and ADMET analysis of coenzyme Q10 as a potential therapeutic agent for Alzheimer's disease
Abdullah Al Noman, Pranab Dev Sharma, Tasmia Jahin Mim, Md Al Azad, Himanshu Sharma
Published: Thursday, December 26, 2024
Viewed: 4138
Get back–calorie restriction: Dr. Masoro’s legacy
Yuji Ikeno, Lisa C. Flores
Published: Thursday, June 30, 2022
Viewed: 4097
Influence of metformin on age-related macular degeneration
Albert J Augustin, Jenny Atorf
Published: Tuesday, May 23, 2023
Viewed: 4075
Influence of metformin on age-related macular degeneration
Albert J Augustin, Jenny Atorf
Published: Tuesday, May 23, 2023
Viewed: 4075
Cardiovascular aging in patients with chronic kidney disease: pathogenesis and potential therapeutics
Safa Alkhayyat, Mohamed Abdalbary, Zahraa Alhoori
Published: Thursday, September 28, 2023
Viewed: 4070
Cardiovascular aging in patients with chronic kidney disease: pathogenesis and potential therapeutics
Safa Alkhayyat, Mohamed Abdalbary, Zahraa Alhoori
Published: Thursday, September 28, 2023
Viewed: 4070
The Eph receptor A4-mediated demyelination in depression
Quanguang Zhang, Luodan Yang
Published: Thursday, December 29, 2022
Viewed: 4051
Carvacrol induces osteogenic differentiation of BMSCs and alleviates osteolysis in aged mice by upregulating lncRNA NEAT1 to promote SIRT1 expression
Zefeng Xu, Zeyu Wang, Wenming Ma, Zhihui Huang
Published: Tuesday, December 26, 2023
Viewed: 3915
Additional polgD257A mutation (mutator) does not influence dopaminergic neurodegeneration in aged parkin-deficient mice
Xin-Ran Zhu, David Mrohs, Max Rybarski, Michael Andriske, Pauline Bohne, Melanie D. Mark, Hermann Lübbert
Published: Tuesday, May 23, 2023
Viewed: 3827
Additional polgD257A mutation (mutator) does not influence dopaminergic neurodegeneration in aged parkin-deficient mice
Xin-Ran Zhu, David Mrohs, Max Rybarski, Michael Andriske, Pauline Bohne, Melanie D. Mark, Hermann Lübbert
Published: Tuesday, May 23, 2023
Viewed: 3827
Proteostasis in aging: mechanistic insights and therapeutic opportunities
Gaurav N. Kasar, Pooja B. Rasal, Chandrashekhar D. Patil, Sunil K. Mahajan, Aman B. Upaganlawar
Published: Thursday, March 6, 2025
Viewed: 3805
On the frontier of immunogerontology—an interview with Prof. Graham Pawelec
Xiaodong Li
Published: Friday, September 30, 2022
Viewed: 3779
Difference in the effectiveness of subthalamic nucleus and globus pallidus deep brain stimulation in Parkinson’s disease
Hushyar Azari
Published: Thursday, June 30, 2022
Viewed: 3754
On the original aspiration of researching neurodegenerative diseases—an interview with Prof. Jeffrey Kordower
Min Zhu
Published: Thursday, December 29, 2022
Viewed: 3754
Fasting helps nutrient sensing systems in clocking the metabolism
Neelu Jain Gupta
Published: Tuesday, June 25, 2024
Viewed: 3740
Fasting helps nutrient sensing systems in clocking the metabolism
Neelu Jain Gupta
Published: Tuesday, June 25, 2024
Viewed: 3740
2021 Reviewer Acknowledgment
Editorial Office of Aging Pathobiology and Therapeutics
Published: Friday, December 31, 2021
Viewed: 3736
The role of immune aging in giant cell arteritis
Patricia Harkins, Sharon Cowley, Robert Harrington, David Kane, Richard Conway
Published: Thursday, September 28, 2023
Viewed: 3680
The role of immune aging in giant cell arteritis
Patricia Harkins, Sharon Cowley, Robert Harrington, David Kane, Richard Conway
Published: Thursday, September 28, 2023
Viewed: 3680
Exploring the interplay of leptin and aging: insights into the role of gut microbiota
Harish Rangareddy, Rajhi Hayfa, Venkateshappa Chikkanarayanappa, Ashakiran Srinivasaiah, Reshma Devarajachar
Published: Friday, April 12, 2024
Viewed: 3665
Exploring the interplay of leptin and aging: insights into the role of gut microbiota
Harish Rangareddy, Rajhi Hayfa, Venkateshappa Chikkanarayanappa, Ashakiran Srinivasaiah, Reshma Devarajachar
Published: Friday, April 12, 2024
Viewed: 3665
On the frontier of chronic obstructive pulmonary disease—an interview with Prof. Peter J Barnes
Wei Ma
Published: Thursday, December 29, 2022
Viewed: 3651
Biological age from a pathological perspective
Warren Ladiges
Published: Wednesday, March 29, 2023
Viewed: 3639
In vitro geroscience. Screening anti-aging drug combinations for neurodegenerative diseases
Warren Ladiges, Soroosh Fatemi, Joo Young Park
Published: Wednesday, June 28, 2023
Viewed: 3621
Older-aged C57BL/6 mice fed a diet high in saturated fat and sucrose for ten months show decreased resilience to aging
Chloe N Johnson, Lida Zhu, Ruby Mangalindan, Jeremy Whitson, Maryia Sweetwyne, Ana P. Valencia, David J. Marcinek, Peter Rabinovitch, Warren Ladiges
Published: Thursday, September 28, 2023
Viewed: 3454
Statins adherence and associated muscle symptoms in elderly coronary heart disease patients
Marat V Ezhov, Marina G. Bubnovaa, David M. Aronov
Published: Tuesday, December 26, 2023
Viewed: 3440
Nrf2 participates in progression of osteoarthritis through modulating redox balance
Yueqi Chen, Zihan Deng, Chuan Yang
Published: Thursday, September 28, 2023
Viewed: 3425
Nrf2 participates in progression of osteoarthritis through modulating redox balance
Yueqi Chen, Zihan Deng, Chuan Yang
Published: Thursday, September 28, 2023
Viewed: 3425
Voluntary wheel running is a non-invasive test to measure physical performance in aging mice
Christina Pettan-Brewer, Addison Keely, Warren Ladiges
Published: Tuesday, December 26, 2023
Viewed: 3395
Is aging “normal”?
Warren Ladiges, Chloe Johnson
Published: Thursday, December 29, 2022
Viewed: 3374
Effects of mitochondrial fusion and fission regulation on mouse hippocampal primary cultures: relevance to Alzheimer's disease
Alina Vadimovna Chaplygina, Daria Yurievna Zhdanova
Published: Friday, April 12, 2024
Viewed: 3336
Effects of mitochondrial fusion and fission regulation on mouse hippocampal primary cultures: relevance to Alzheimer's disease
Alina Vadimovna Chaplygina, Daria Yurievna Zhdanova
Published: Friday, April 12, 2024
Viewed: 3336
The case of a geriatric female experiencing frequent falls and epileptic seizures during long-term low-dose clozapine and extended-release bupropion treatment
Charisse Dzierba, Claudia Lee, Tammie Lee Demler
Published: Wednesday, June 28, 2023
Viewed: 3315
Serum elementomic analysis indicates a panel of elements related with age
Hui-Xian Sun, Kai-Yue Jia, Yan-Ru Li, Can Zhao, Xiang Lu, Wei Gao
Published: Friday, February 23, 2024
Viewed: 3262
Research advances in stem cell transplantation combined with fibrin scaffold for treating spinal cord injury in an aging society
Yongxiong He, Tianqi Jiang, Zhijun Chen, Yitong Luo, Xinyue Tian, Hua Yang
Published: Thursday, March 7, 2024
Viewed: 3258
Ethylnitrosourea-induced gliomas: a song in the attic?
Yuji Ikeno
Published: Wednesday, June 28, 2023
Viewed: 3232
Exploring the complex interplay between anxiety, aging, and behavior in CB6F1 and C57BL/6 mice: implications for cognitive function
Gerald Yu Liao, Kunyuan Li, Addison Keely, Shuliang Yu, Christina Pettan-Brewer, Warren Ladiges
Published: Monday, March 25, 2024
Viewed: 3173
Inflammaging and microbiota: the intersection of aging, inflammation, and gut health
Harish Rangareddy, Jessica Fryer, Achal Shetty, Hayfa Rajhi
Published: Friday, June 27, 2025
Viewed: 3134
Gut microbiome and neurodegenerative disorders: therapeutic Implications
Sugato Banerjee, Ritika Ruwatia, Suparna Roy Sarkar, Subhamoy Panda
Published: Thursday, November 21, 2024
Viewed: 2995
Gut microbiome and neurodegenerative disorders: therapeutic Implications
Sugato Banerjee, Ritika Ruwatia, Suparna Roy Sarkar, Subhamoy Panda
Published: Thursday, November 21, 2024
Viewed: 2995
Biobased nanoemulsions for targeted drug delivery to treat dementia and aging
Joseph S. D'Arrigo
Published: Thursday, September 28, 2023
Viewed: 2956
Biobased nanoemulsions for targeted drug delivery to treat dementia and aging
Joseph S. D'Arrigo
Published: Thursday, September 28, 2023
Viewed: 2956
Diverse models in Alzheimer's research: exploring alternative approaches beyond traditional rodent frameworks
Govind Singh, Payal Chauhan, Karan Wadhwa
Published: Thursday, December 26, 2024
Viewed: 2946
Physical resilience is a predictor of healthy aging
Warren Ladiges
Published: Thursday, September 28, 2023
Viewed: 2844
Modeling resilience to sleep disruption to study resistance to Alzheimer’s disease
Warren Ladiges, Jordan Mazzola, Joo Young Park
Published: Tuesday, December 26, 2023
Viewed: 2838
On the treatment of Parkinson’s disease—an interview with Prof. Nir Giladi
Siyan Chen
Published: Tuesday, December 26, 2023
Viewed: 2786
On epigenetic clocks and cancer risk—an interview with Prof. Andrew E. Teschendorf
Shikha Sharma
Published: Tuesday, December 26, 2023
Viewed: 2756
Cigarette exposure and aging pathways: interplay between IGF-1 suppression and TGF-β increase
Titiek Hidayati, Akrom Akrom, Suny Sun
Published: Sunday, September 28, 2025
Viewed: 2722
Cartilage organoid model of osteoarthritis to study aging-related diseases
Guangxuan Yan, Yongxiong He, Zhiqiang Shi, Yuan Li, Kai Tao, Jun Fan, Qiankun Zhu, Heng Wang, Aitao Wang, Yongchao Li
Published: Friday, June 27, 2025
Viewed: 2626
Impact of oral vitamin D3 supplementation on proximal femur fracture incidence in the elderly population
Hao Liu, Qingjun Qiu, Xuwen Luo, Bin Yuan
Published: Thursday, June 20, 2024
Viewed: 2613
Resilience to aging drives personalized intervention strategies for Alzheimer’s disease
Warren Ladiges, Jackson Wezeman, Addison Keely
Published: Tuesday, December 26, 2023
Viewed: 2600
On the growth of young geriatricians——an interview with Prof. Louis R. Caplan
Chan Rong
Published: Friday, December 1, 2023
Viewed: 2571
Importance of coordination of regional stroke centers for acute ischemic stroke
Xin Xu, Yingjun Ouyang, Chan Rong
Published: Tuesday, December 26, 2023
Viewed: 2560
Experimental confirmation of osteoarthritis repair in vivo using epigenetic reprogramming with small molecules
Javdat N. Muratkhodjaev, Saodat A. Muratkhodjaeva, Tamara U. Aripova
Published: Monday, September 8, 2025
Viewed: 2435
Beyond hallmarks of aging – biological age and emergence of aging networks
S. Michal Jazwinski, Sangkyu Kim, Jessica Fuselier
Published: Monday, March 31, 2025
Viewed: 2423
Beyond hallmarks of aging – biological age and emergence of aging networks
S. Michal Jazwinski, Sangkyu Kim, Jessica Fuselier
Published: Monday, March 31, 2025
Viewed: 2423
2022 Reviewer Acknowledgment
Editorial Office of Aging Pathobiology and Therapeutics
Published: Thursday, December 29, 2022
Viewed: 2388
Integrative bioinformatics and molecular docking unveil multi-target therapeutic mechanisms of Coptidis Rhizoma (CR) against Lewy body dementia (LBD): an in-silico approach
Pranab Dev Sharma, Abdullah Al Noman
Published: Friday, June 6, 2025
Viewed: 2341
The role of epigenetics in cognitive aging: mechanisms, interventions, and future directions
Abdullah Al Noman, Pranab Dev Sharma, Himanshu Sharma
Published: Friday, June 27, 2025
Viewed: 2320
Epigenetic mechanisms of the influence of aging on the development of breast cancer with the participation of retroelements
Rustam Nailevich Mustafin
Published: Friday, August 15, 2025
Viewed: 2316
Epigenetic mechanisms of the influence of aging on the development of breast cancer with the participation of retroelements
Rustam Nailevich Mustafin
Published: Friday, August 15, 2025
Viewed: 2316
Pharmacologic activation of delta133p53α reduces cellular senescence in progeria patients-derived cells
Sebastien M. Joruiz, Patricia K. Dranchak, Natalia Von Muhlinen, Curtis C. Harris, Izumi Horikawa, James Inglese, Delphine Lissa
Published: Tuesday, September 16, 2025
Viewed: 2266
2023 Reviewer Acknowledgment
Editor Office of Aging Pathobiology and Therapeutics
Published: Tuesday, December 26, 2023
Viewed: 2256
Resilience in the depths: anemones as models for aging and regeneration research
Pooja B. Rasal, Gaurav N. Kasar, Durgesh S. Pagar, Aman B. Upaganlawar, Sunil K. Mahajan
Published: Friday, July 18, 2025
Viewed: 2236
Periodontal disease, cardiovascular diseases and aging-the multidirectional link
Madhurya N Kedlaya, Reshma Suresh, Maya Rajan Peter, Lakshmi Puzhankara
Published: Tuesday, June 25, 2024
Viewed: 2221
Periodontal disease, cardiovascular diseases and aging-the multidirectional link
Madhurya N Kedlaya, Reshma Suresh, Maya Rajan Peter, Lakshmi Puzhankara
Published: Tuesday, June 25, 2024
Viewed: 2221
Stricter definitions of myeloid senescence are needed
Brandt D. Pence
Published: Tuesday, June 18, 2024
Viewed: 2216
Myrmecodia platytyrea tuber aqueous extract exacerbates neuroinflammation
Mizaton Hazizul Hasan, Aisyah Hasyila Jahidin, Hanish Singh Jayasingh Chellammal, Ayuni Nordin, Suraya Suratman, Mohd Faiz Mustaffa
Published: Monday, February 10, 2025
Viewed: 2213
Myrmecodia platytyrea tuber aqueous extract exacerbates neuroinflammation
Mizaton Hazizul Hasan, Aisyah Hasyila Jahidin, Hanish Singh Jayasingh Chellammal, Ayuni Nordin, Suraya Suratman, Mohd Faiz Mustaffa
Published: Monday, February 10, 2025
Viewed: 2213
Improving human reproductive health and fertility——an interview with Prof. Marco G. Alves
Zijian Tian
Published: Thursday, May 30, 2024
Viewed: 2211
Effect of dual task training versus analogy training on gait speed and balance in older adults—randomized controlled trial
Yashi Shah, Reema Joshi, Chetana Tetgure
Published: Saturday, December 14, 2024
Viewed: 2208
Focus on cytomegalovirus and cardiovascular diseases——an interview with Prof. Patricia Price
Ying Li, Jianwen Chen, Yujing Fang
Published: Tuesday, June 11, 2024
Viewed: 2187
From plants to potential therapeutics: exploring neuroprotective properties against Alzheimer’s disease through molecular docking and MD simulations
Ashwani Kumar, Shubham Kumar, Aanchal Gupta, Chirag N. Patel, Vikas Kumar
Published: Friday, June 27, 2025
Viewed: 2164
A mechanistic narrative review of phytochemical enhancement of mitophagy in Parkinson’s disease: from PINK1/Parkin pathways to dopaminergic neuroprotection
Peace Ayo Olaoluwa, Abraham Olufemi Asuku, Patrick Oluwole Abolarin, Ayodeji Johnson Ajibare, Gideon Opeyemi Ayilara
Published: Tuesday, March 31, 2026
Viewed: 2139
Exploring the neuroprotective potential of an iota-carrageenan in in vitro Parkinson's disease model: evaluation of pharmacological safety, antioxidant properties, and mitochondrial function
Ricardo Basto Souza, Joana Silva, Celso Alves, Agnieszka Zofia Neugebauer, Vitória Virgínia Magalhães Soares, Raimundo Rafael de Almeida, Nágila Maria Pontes Silva Ricardo, Norma Maria Barros Benevides, Rui Pedrosa
Published: Monday, February 10, 2025
Viewed: 2070
Exploring the neuroprotective potential of an iota-carrageenan in in vitro Parkinson's disease model: evaluation of pharmacological safety, antioxidant properties, and mitochondrial function
Ricardo Basto Souza, Joana Silva, Celso Alves, Agnieszka Zofia Neugebauer, Vitória Virgínia Magalhães Soares, Raimundo Rafael de Almeida, Nágila Maria Pontes Silva Ricardo, Norma Maria Barros Benevides, Rui Pedrosa
Published: Monday, February 10, 2025
Viewed: 2070
Heart rate recovery under healthy aging or age-related pathologies
Anton R. Kiselev
Published: Tuesday, December 30, 2025
Viewed: 2036
Machine learning paves the way forward for geropathology assessment
Gerald Yu Liao, Jenna Klug, Warren Ladiges
Published: Tuesday, June 4, 2024
Viewed: 2025
The microgram hypothesis: a translational dosing error in Epitalon peptide research and its implications for human aging application
Chang-Hun Jung
Published: Tuesday, June 30, 2026
Viewed: 2023
Expanding the clinical implications of biomarkers and physiological indicators in geriatric institutionalization
Jitendra Kumar Sinha, Shampa Ghosh, Krishna Kumar Singh
Published: Thursday, September 11, 2025
Viewed: 1972
Effects of structured group reminiscence in sports and non-sports environments on cognitive empowerment and optimism in older adults: a quasi-experimental study
Bahador Azizi, Amin Azimkhani, Mohammad Khazaei, Saleh Moazam, Nazli Ilchizadeh, Katarzyna Dzioban
Published: Friday, June 27, 2025
Viewed: 1903
Effect of continuous illumination on the ultrastructure of rat hepatocytes during ontogenesis
David A. Areshidzea, Maria A Kozlova
Published: Friday, September 12, 2025
Viewed: 1887
Targeting metabolic function to improve aging and healthspan: 2024 Masoro-barshop conference on aging
Adam Salmon
Published: Thursday, December 26, 2024
Viewed: 1854
Two-sample mendelian randomization study: vitamin D levels and chronic kidney disease in the elderly population
Ling Xiao, Kaiping Luo, Honghong Zou
Published: Sunday, September 29, 2024
Viewed: 1809
The promise of adult neurogenesis for treating and preventing chronic neurodegenerative diseases
Warren Ladiges, Gerald Yu Liao
Published: Friday, September 13, 2024
Viewed: 1801
Endotoxin-induced acute lung injury in old C57BL/6J mice is a translationally relevant geroscience model
Warren Ladiges, Qianpei He, Ruby S. Mangalindan, Jenna Klug
Published: Tuesday, March 18, 2025
Viewed: 1779
Autophagy in neurodegeneration: recent advances, autophagosome formation, and therapeutic innovations—an interview with Prof. David Rubinsztein
Aracely Garcia-Garcia
Published: Thursday, December 26, 2024
Viewed: 1770
Towards clinical translation of biomarkers and therapies targeting autolysosomal acidification dysfunction in neuroinflammation and neurodegeneration—an interview with Prof. David Rubinsztein
Chih Hung Lo
Published: Sunday, September 29, 2024
Viewed: 1729
Sarcopenia and intrinsic capacity in aging: implications for geriatric physiotherapy assessment and care
Weslley Barbosa Sales, Melissa Silva Rocha Pereira
Published: Friday, August 29, 2025
Viewed: 1703
An aged rodent tissue bank fills unmet needs for biomedical research on aging
Warren Ladiges
Published: Tuesday, December 30, 2025
Viewed: 1692
A natural way for a healthier lifestyle—an interview with Prof. Stephen C. Bondy
Alessandro Bitto
Published: Friday, August 16, 2024
Viewed: 1670
Accelerated biological ageing in type 2 diabetes mellitus: mechanistic, cellular, and systemic perspectives
Simran C. Yadav, Shraddha V. Mahale, Sneha M. Nishad, Bhumika D. Bankar, Pooja B. Rasal
Published: Tuesday, March 31, 2026
Viewed: 1653
Metabolic dysfunction-associated steatotic liver disease of older people
Chieh Chen, Da-Ming Liao
Published: Friday, August 16, 2024
Viewed: 1630
Metabolic dysfunction-associated steatotic liver disease of older people
Chieh Chen, Da-Ming Liao
Published: Friday, August 16, 2024
Viewed: 1630
Revisiting mitochondrial dysfunction in aging biology research
Brandt D. Pence, Yufeng Zhang
Published: Monday, March 24, 2025
Viewed: 1619
A change is needed in the landscape of preclinical models to test drugs that target aging
Warren Ladiges
Published: Thursday, December 26, 2024
Viewed: 1562
Predicting resilience to aging with physical stressors
Warren Ladiges
Published: Friday, September 26, 2025
Viewed: 1506
Low- vs high-load power training on muscle quality, functional performance, and multi-omic profiles in frail older adults: protocol for the FrailPow randomized controlled trial
Xabier Mateos-Marañón, Iñaki Martín-Lesende, Arkaitz Larrinaga-Undabarrena, José Ramón Sánchez-Isla, Aitor Santisteban-Leguina, Iker Muñoz-Pérez, Iker Sáez, Oihana Hernández Ortiz de Urbina, Amaia Fernandez Alonso, Ana María López Rodríguez, Celia Aragón Ferrao, Irene Gómez Soto, Xabier Río
Published: Tuesday, March 31, 2026
Viewed: 1436
No causal effect of olive oil consumption on Alzheimer’s disease: a two-sample Mendelian randomization with mediation and multivariable analyses
Muhammad Iqhrammullah, Teuku Fais Duta, Derren DCH Rampengan, Nuril Farid Abshori, Bryan Gervais de Liyis, Fahrul Nurkolis
Published: Tuesday, December 30, 2025
Viewed: 1396
2024 Reviewer Acknowledgment
Editor Office of Aging Pathobiology and Therapeutics
Published: Thursday, December 26, 2024
Viewed: 1390
Non-drug therapy for sleep disorders in the elderly: a focus on neurofeedback technology
Igor Shirolapov, Alexander Zakharov
Published: Tuesday, March 31, 2026
Viewed: 1370
The neuropathology of aging and Alzheimer’s disease in domestic cats
Warren Ladiges, Ankita Sharma
Published: Friday, June 27, 2025
Viewed: 1362
The estimation of the clinical status of the residents in a geriatric health service facility in Japan
Toyoki Maeda
Published: Friday, June 27, 2025
Viewed: 1328
Dysregulation of Nrf2/ARE pathway and mitochondrial DNA damage in aging and Alzheimer’s-associated cognitive decline
Polina I. Babenkova, Veronika V. Nesterova, Arina D. Tsvetkova, Anna A. Eremina, Artem P. Gureev, Vera A. Kryukova, Irina S. Sadovnikova
Published: Tuesday, December 30, 2025
Viewed: 1297
The loss of methionine sulfoxide reductases significantly suppresses tumor development and exacerbates kidney pathology in male quadruple Msr knockout mice
Ganga Tandukar, Lisa C. Flores, Colton Allen, Yidong Bai, Jonathan Gelfond, Yuji Ikeno, Adam Salmon
Published: Tuesday, December 30, 2025
Viewed: 1226
Non invasive techniques for muscle quality functional domain monitoring in older adults: a scoping review
Naiara Virto, Xabier Río, Amaia Méndez-Zorrilla, Begoña García-Zapirain
Published: Tuesday, March 31, 2026
Viewed: 1221
Non invasive techniques for muscle quality functional domain monitoring in older adults: a scoping review
Naiara Virto, Xabier Río, Amaia Méndez-Zorrilla, Begoña García-Zapirain
Published: Tuesday, March 31, 2026
Viewed: 1221
Successful aging through integrative nutrition: a four-pillar framework for deprescribing and resilience
Mehrshad Fahim Devin, Mikhail Kogan, Frame A. Leigh, Lindsey Gordon, Zeynep Celikkol, Ruhsen Ozcaglayan
Published: Tuesday, March 31, 2026
Viewed: 1199
Successful aging through integrative nutrition: a four-pillar framework for deprescribing and resilience
Mehrshad Fahim Devin, Mikhail Kogan, Frame A. Leigh, Lindsey Gordon, Zeynep Celikkol, Ruhsen Ozcaglayan
Published: Tuesday, March 31, 2026
Viewed: 1199
Associations between physical activity patterns and quality of life among hypertensive older adults: a logistic and principal component analysis
Sarah Nadiya, Abdul Gani, Sri Andala, Meutia Zahra, Agusri Agusri, Liza Wahyuni
Published: Tuesday, March 31, 2026
Viewed: 1181
Hecogenin, a plant-derived small molecule, as a potential therapeutic intervention for neurodegenerative disorders: insights from a zebrafish model
Shametha Francis Xavier, Sanjaai K M, Deepthi Padmanabhan, Anith Kumar Rajendran, Senthilkumar Palanisamy
Published: Tuesday, December 30, 2025
Viewed: 1161
Biomarkers for prognostic stratification in chronic heart failure in older patients
Anton R. Kiselev, Kseniya D. Dorogoykina
Published: Friday, June 27, 2025
Viewed: 1148
L-Fucose is a promising gerotherapeutic drug
Warren Ladiges, Jackson Wezeman, Addison Keely
Published: Tuesday, December 30, 2025
Viewed: 1115
Dietary approaches to geroscience intervention: 2025 Masoro-Barshop Conference on aging
Adam Salmon
Published: Tuesday, December 30, 2025
Viewed: 1111
From biology of reproduction to biology of aging
Andrzej Bartke
Published: Tuesday, March 31, 2026
Viewed: 1090
Targeting amyloid aggregation with ethanol extracts of fermented Swietenia macrophylla: a metabolomic and molecular docking approach
Agustina Lulustyaningati Nurul Aminin, Bayu Fajriansyah Al-Khairi, Mukhammad Asy’ari, Muhammad Ajmal Shah
Published: Tuesday, December 30, 2025
Viewed: 1045
Untreated hip fracture as a trigger for rapid frailty progression: a case report
Mayang Rizki Anggraeni, Etha Dini Widiasi, Novira Widajanti
Published: Tuesday, December 30, 2025
Viewed: 1023
Prevalence of geriatric syndromes in patients with advanced dementia cared for by a Geriatric Home Care Unit
Arís Somoano Sierra, Blanca Garmendia Prieto, Francisco Sánchez del Corral Usaola, Javier Gómez Pavón
Published: Tuesday, March 31, 2026
Viewed: 1018
A half-century history of aging research in San Antonio
Ganga Tandukar, Lisa C. Flores, Colton Allen, Yuji Ikeno
Published: Tuesday, December 30, 2025
Viewed: 999
Geropathology is a common denominator for multispecies research in geroscience, from insects to nonhuman primates
Jenna Klug, Warren Ladiges
Published: Tuesday, March 31, 2026
Viewed: 996
Rethinking morphine for neuropathic pain in the elderly: a neuroimmune perspective on preclinical evidence and clinical caution
Shima Hashemi, Bahareh Lashtoo Aghaee, Samaneh Farrokhfar
Published: Tuesday, March 31, 2026
Viewed: 993
Medicinal plants and healthy aging: an urgent call for robust clinical evidence
Emad M. Abdallah, Wael E. Abdalla, Alaa M.M. Sadeek
Published: Tuesday, December 30, 2025
Viewed: 984
Neuroprotective effect of aldehyde trapping agent, hydralazine, in a Parkinson’s disease mouse model
Elizabeth Fernandez, Margaret Chia-Ying Wey, Paul Anthony Martinez, Patricia Sullivan, David Goldstein, Randy Strong
Published: Tuesday, March 31, 2026
Viewed: 799
mTOR signaling in aging and longevity: therapeutic opportunities
Gaurav N. Kasar, Pooja B. Rasal, Aman B. Upaganlawarb, Manoj S Mahajan
Published: Tuesday, June 30, 2026
Viewed: 614
Sensory reweighting patterns and fall history in early geriatric age: implications for physiotherapy assessment
Wittaya Duangnga
Published: Tuesday, June 30, 2026
Viewed: 548
Role of miR-140-5p in vascular aging and arterial stiffening: a review of potential mechanisms
Muhammad Iqhrammullah, Ayers GI Kalaij, Vindasya Almeira, Febi Septiani, Priscilla CNBR Sirait, I Made Dwi Mertha Adnyana, Keviano Bobby, Sania Zahrani, Derren DCH Rampengan
Published: Tuesday, June 30, 2026
Viewed: 470
Disrupted calcium homeostasis: a hidden driver of cellular aging
Patricia Pantoja Newman, Brandt D. Pence
Published: Tuesday, June 30, 2026
Viewed: 440
Approximate prediction of life expectancy in the older people using a revised equation for estimating somatic telomere length from clinical blood data
Toyoki Maeda
Published: Tuesday, June 30, 2026
Viewed: 416
Senotherapeutic potential of Mediterranean diet-derived bioactives in healthy aging and frailty
Sedat Arslan
Published: Tuesday, June 30, 2026
Viewed: 398
Senotherapeutic potential of Mediterranean diet-derived bioactives in healthy aging and frailty
Sedat Arslan
Published: Tuesday, June 30, 2026
Viewed: 398
Targeting ageing: the next frontier in drug delivery systems
Rajaram Mohapatra, Pratikeswar Panda
Published: Tuesday, June 30, 2026
Viewed: 395
Brain iron in ageing: Pixels to pathways
Thomas Welton
Published: Tuesday, June 30, 2026
Viewed: 385
Brain iron in ageing: Pixels to pathways
Thomas Welton
Published: Tuesday, June 30, 2026
Viewed: 385
Voluntary wheel running enhances neuronal BDNF in very old C57BL/6 mice
Gina Israel, Ruby Sue Mangalindan, Warren C Ladiges, Addison Keely
Published: Tuesday, June 30, 2026
Viewed: 376
Low-dose radiotherapy for severe osteoarthritis refractory to conservative treatment in older adults: an underexplored option
Jorge Andrés Sánchez Duque, María Camila Fernández-Gualdron, Miguel M Moreno-Capacho, Holman Duvan Ballesteros-Gomez
Published: Tuesday, June 30, 2026
Viewed: 373
Genetic drift and selective pressures shaping mitochondrial ND3 variants m.10398A>G and m.10400C>T: implications for type 2 diabetes risk in Indian population
Jwalant Waghmare, Tejas Tajane, Mamata Chandrakar, Prafulla Ambulkar, Pranita Waghmare, Bharati Taksande
Published: Tuesday, June 30, 2026
Viewed: 363
Countering oxysterol-driven neurodegeneration: diosgenin as a privileged steroidal scaffold for novel Alzheimer’s disease therapeutics
Sarvesh Sabarathinam
Published: Tuesday, June 30, 2026
Viewed: 350
Countering oxysterol-driven neurodegeneration: diosgenin as a privileged steroidal scaffold for novel Alzheimer’s disease therapeutics
Sarvesh Sabarathinam
Published: Tuesday, June 30, 2026
Viewed: 350
The association of post-traumatic stress disorder with accelerated aging
Anton R. Kiselev
Published: Tuesday, June 30, 2026
Viewed: 300