• 电子竞技的兴起改变了传统体育和娱乐行业的格局。
  • 随着人们对健康意识的提高,健康食品和生活方式受到更多关注。
  • 太空探索的商业化为航天产业带来了新的增长点。
  • 远程工作已成为许多行业新的常态,改变着职场文化。
  • 加密货币市场的波动引发了对金融监管的新讨论。
  • 随着全球变暖的加剧,极端天气事件变得更加频繁。
  • 海洋塑料污染问题引起了全球范围内的广泛关注。
  • 在线教育的普及为全球学习者提供了更多样化的学习资源。
  • 可持续发展是解决环境问题的关键。
  • 教育改革成为各国政府关注的热点议题。
  • 全球健康危机加速了医疗保健行业的数字化转型。
  • 社交媒体在政治动员和社会运动中的作用越来越显著。
  • 数字货币的兴起正在改变金融交易的方式,引发监管机构的关注。
  • 电子竞技的流行正在改变传统体育和娱乐行业的格局。
  • 生物技术在医药领域的应用带来了新的突破和挑战。
  • 随着人们对健康意识的提高,健康食品和生活方式受到更多关注。
  • 大数据和机器学习在商业决策中的作用越来越重要。
  • 人工智能技术的融合正在推动医疗、工业和服务业的创新。
  • 新能源汽车市场的快速增长改变了汽车行业的格局。
  • 气候变化问题日益严峻,国际社会加大了对减排和可持续发展的关注。
  • 隐私保护和数据安全成为数字时代的重要议题。
  • 在线教育的兴起为教育资源的公平分配提供了新途径。
  • 自动化和机器人技术在提高生产效率和降低成本方面取得显著进展。
  • 远程医疗的普及使得医疗服务更加便捷,尤其是在偏远地区。
  • 随着全球对COVID-19疫情的持续应对,远程工作已成为新常态。
  • More NIH
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    Review Evidence for an alternative insulin transporter at the blood-brain barrier Elizabeth M Rhea, William A Banks, Cassidy Noonan Published: Tuesday, May 23, 2023
    Review Evidence for an alternative insulin transporter at the blood-brain barrier Elizabeth M Rhea, William A Banks, Cassidy Noonan Published: Tuesday, May 23, 2023
    Therapeutic Brief GHK peptide prevents sleep deprived learning impairment in aging mice Warren Ladiges, Manuela Rosenfeld, Katie Nickel Published: Wednesday, March 29, 2023
    Model Profile The CB6F1 mouse is a model for studying cognition and brain morphometry with increasing age Warren Ladiges, Davika Gandhay, Christina Pettan Brewer Published: Wednesday, March 29, 2023
    Commentary The Eph receptor A4-mediated demyelination in depression Quanguang Zhang, Luodan Yang Published: Thursday, December 29, 2022
    Editorial Is aging “normal”? Warren Ladiges, Chloe Johnson Published: Thursday, December 29, 2022
    Commentary Targeting IGF1R signaling for brain aging and Alzheimer’s disease Warren Ladiges, Joo Young Park, Martin Darvas Published: Thursday, December 29, 2022
    Model Profile A mouse model of naturally occurring age-related cognitive impairment Sara Daneshjoo, Jualiana Moreno, Manuela Rosenfeld, Joo Young Park, Martin Darvas, Warren Ladiges Published: Friday, September 30, 2022
    Commentary Sex Matters in Aging. The Canagliflozin Story Warren Ladiges, Jackson Wezeman Published: Friday, September 30, 2022
    Research Article Long-term treatment with Elamipretide enhances healthy aging phenotypes in mice Kaitlin Nickel, Lida Zhu, Ruby Mangalindan, Jessica M. Snyder, Jeremy Whitson, Maryia Sweetwyne, Ana P. Valencia, Jenna Klug, Zhou Jiang, David J. Marcinek, Peter Rabinovitch, Warren Ladiges, Matthew Tucker Published: Friday, September 30, 2022
    Editorial Get back–calorie restriction: Dr. Masoro’s legacy Yuji Ikeno, Lisa C. Flores Published: Thursday, June 30, 2022
    Commentary Pharmaceutical interventions to slow human aging. Are we ready for cocktails? Warren Ladiges, Manuela Rosenfeld Published: Thursday, June 30, 2022
    Commentary Geropathology. An inside view of biological aging Warren Ladiges Published: Wednesday, March 30, 2022
    Editorial Microbiome in aging of Gut and Brain (MiaGB): paving the ways to understand gut-brain axis in aging Michal M. Masternak, Hariom Yadav Published: Wednesday, March 30, 2022
    Commentary Resilience to aging is a heterogeneous characteristic defined by physical stressors Haoyi Lei, Derek M. Huffman, Adam B. Salmon, Nathan K. LeBrasseur, Christy Carter, Arlan Richardson, Steve Austad, Warren Ladiges Published: Wednesday, March 30, 2022
    Research Article PathoClock and PhysioClock in mice recapitulate human multimorbidity and heterogeneous aging Warren Ladiges, Shabnam Salimi, Christina Pettan-Brewer Published: Friday, December 31, 2021
    Commentary The unrecognized potential of pet cats for studying aging and age-related diseases Warren Ladiges Published: Friday, December 31, 2021
    Conference Abstract The aging immune system. Abstracts presented at the Masoro-Barshop conference on aging, October 13-15, 2021 Warren Ladiges Published: Friday, December 31, 2021
    Commentary Mouse modeling for anxiety disorders in older adults Martin Darvas, Warren Ladiges, Nadia Postupna Published: Thursday, September 30, 2021
    Therapeutic Brief The antidiabetic drug acarbose suppresses age-related lesions in C57BL/6 mice in an organ dependent manner Zhou Jiang, Sneh Gupta, Warren Ladiges Published: Tuesday, June 29, 2021
    Commentary Precision aging. Human lifespan has intrinsic limits but measurable outcomes Warren Ladiges Published: Tuesday, June 29, 2021
    Editorial Thioredoxin – a magic bullet or a double-edged sword for mammalian aging? Yuji Ikeno Published: Tuesday, June 29, 2021
    Therapeutic Brief Physical performance is enhanced in old mice fed a short term diet medicated with rapamycin, acarbose, and phenylbutyrate Warren Ladiges, Megan Ellis, Zhou Jiang Published: Monday, March 29, 2021
    Editorial Harnessing the heterogeneity of aging Warren Ladiges Published: Monday, March 29, 2021
    Geropathology Notes Hepatic steatosis, a lesion reported in captive aged common marmosets Sebastian Eduardo Carrasco, Olga Lucia Franco-Mahecha Published: Monday, March 29, 2021
    Case Report Spontaneous chordoma: a case report on a female UM-HET3 mouse from the SLAM study Eleonora Duregon, Rafael de Cabo, Camila Vieira Ligo Teixeira, Dushani L. Palliyaguru, Annamaria L. Rudderow, Victoria Hoffmann, Michel Bernier, Nathan L. Price, Simonetta Camandola Published: Thursday, December 31, 2020
    Model Profile Neutrophil response to cyclophosphamide predicts resilience to age-related learning impairment Lida Zhu, Warren Ladiges, Katie Nickel, Marianne Bjorner Published: Thursday, December 31, 2020
    Geropathology Notes Eosinophilic crystalline pneumonia, an age-related lesion in mice Jenna J Klug, Jessica M Snyder Published: Thursday, December 31, 2020
    Research Article Sex-dependent lifespan extension of ApcMin/+ FAP mice by chronic mTOR inhibition Manish Parihar, Sherry G Dodds, Marty Javors, Randy Strong, Paul Hasty, Zelton Dave Sharp Published: Thursday, December 31, 2020
    Research Article Resilience to acute sleep deprivation is associated with attenuation of hippocampal mediated learning impairment Warren Ladiges, Amanda Lee, Haoyi Lei, Lida Zhu, Zhou Jiang Published: Thursday, December 31, 2020
    Research Article Thioredoxin down-regulation in the cytosol in thioredoxin 2 transgenic mice did not have beneficial effects to extend lifespan in male C57BL/6 mice Lisa C. Flores, Madeline G. Roman, Geneva M. Cunningham, Christie Cheng, Colton Allen, Yidong Bai, Gene B. Hubbard, Yuji Ikeno Published: Thursday, December 31, 2020
    Model Profile A model for studying cutaneous wound healing and resilience to aging: Ear punch biopsy in old mice Warren Ladiges, Zhou Jiang, Jessie Chen, Juan Wang, Ruby Mangalindan, Lida Zhu Published: Tuesday, September 29, 2020
    Therapeutic Brief Short-term oral rapamycin prevents age-related learning impairment in mice Warren Ladiges, Haoyi Lei, Juan Wang, Zhou Jiang Published: Tuesday, September 29, 2020
    Technology Feature An immune stress test for resilience to aging: Pneumococcal vaccine response Warren Ladiges, Ryan Oveson, Zhou Jiang, Michali Izhak, Kavita Sharma Published: Tuesday, September 29, 2020
    Review Aging pet cats develop neuropathology similar to human Alzheimer’s disease Warren Ladiges, Jenna Klug, Jessica M. Snyder, Martin Darvas, Denise M. Imai, Molly Church, Caitlin Latimer, C . Dirk Keene Published: Tuesday, September 29, 2020
    Review Thioredoxin and aging: What have we learned from the survival studies? Lisa C. Flores, Madeline G. Roman, Geneva M. Cunningham, Christie Cheng, Colton Allen, Gene Borden Hubbard, Yidong Bai, Thomas L. Saunders, Yuji Ikeno Published: Tuesday, September 29, 2020
    Case Report Novel LMNA mutations in Greek and Myanmar Patients with Progeroid Features and Cardiac Manifestations Junko Oshima, Renuka Kandhaya-Pillai, Fuki M Hisama, Stephanie A Bucks, Soe Yarzar, Haroula Korovou, George M Martin Published: Monday, June 29, 2020
    Technology Feature QuPath. A new digital imaging tool for geropathology Warren Ladiges, Amanda Lee, Zhou Jiang, Lida Zhu Published: Monday, June 29, 2020
    Therapeutic Brief The potential of GHK as an anti-aging peptide Warren Ladiges, Yan Dou, Amanda Lee, Lida Zhu, John Morton Published: Friday, March 27, 2020
    Research Article Mitochondrial-targeted methionine sulfoxide reductase overexpression increases the production of oxidative stress in mitochondria from skeletal muscle Adam B. Salmon, Arunabh Bhattacharya, Daniel Pulliam, Yuhong Liu Published: Friday, March 27, 2020
    Review Development of a Geropathology Grading Platform for nonhuman primates Warren Ladiges, Katie J Olstad, Denise M Imai, Rebekah I Keesler, Rachel Reader, John H Morrison, Jeffery A Roberts, John P Capitanio, Elizabeth S Didier, Marcelo J Kuroda, Heather Simmons, Shabnam Salimi, Julie A Mattison, Yuji Ikeno Published: Friday, March 27, 2020
    Research Article Thioredoxin overexpression in mitochondria showed minimum effects on aging and age-related diseases in male C57BL/6 mice Madeline G. Roman, Lisa C. Flores, Geneva M. Cunningham, Christie Cheng, Sara Dube, Colton Allen, Holly Van Remmen, Yidong Bai, Thomas L. Saunders, Yuji Ikeno Published: Friday, March 27, 2020
    Conference Abstract Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging Warren Ladiges, Yuji Ikeno, Liang Wang Published: Friday, March 27, 2020
    Research Article Sleep-deprived cognitive impairment in aging mice is alleviated by rapamycin Warren Ladiges, Kishore Mukherjee, Amanda Lee, Lida Zhu, Martin Darvas Published: Monday, December 30, 2019


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